New research has advanced understanding of how the nucleolus is assembled through a process called liquid-liquid phase separation and has identified a protein that plays key role Researchers have ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

Deep within the nucleus of every cell lies a structure smaller than a pinpoint that may hold the secret to aging. Scientists at Weill Cornell Medicine have discovered that the nucleolus, long known ...

Although known since the 1830s as a round, dark spot in a cell's nucleus, only recently has the nucleolus gotten its full due. Scientists have learned that besides building a cell's protein factories, ...

Striking nucleolar lesions occur in cultured cells after exposure to supranormal temperatures. These lesions appear at 42°C and consist of a loss of the granular ribonucleoprotein (RNP) component and ...

THE nucleolus was first figured in 1781 as a spot in the centre of a round or oval body (the nucleus) in epithelial cells of the eel. Since then it has been described in the nuclei of almost every ...

Inside all living cells, loosely formed assemblies known as biomolecular condensates perform many critical functions. However, it is not well understood how proteins and other biomolecules come ...