Telomere maintenance is critical for genome stability. The newly-identified Ctc1/Stn1/Ten1 complex is important for telomere maintenance, though its precise role is unclear. We report here that ...

If the engines of DNA replication stay in high gear all the time, they eventually stall or even break down. Fortunately, these engines, which consist of protein complexes, have what could be called ...

DNA replication is a basic function of living organisms, allowing cells to divide and multiply, all while maintaining the genetic code and proper function of the original cell. The process, or ...

Undergraduate biology students could be forgiven for thinking that scientists have DNA replication all figured out. After all, textbooks present the models of replication so matter-of-factly that it's ...

This video shows replication of individual pieces of double stranded DNA. This is the first time DNA replication -- arguably, the fundamental process of life on Earth -- has been observed directly.

Overview: My research career was devoted to helping to establish the central principals of cellular DNA replication, ranging from mechanisms of nucleotide biosynthesis to the complex interplay of ...

As DNA strands ravel and unravel in an intricate dance, one notable event takes center stage: replication. This process is essential to life, but the finer details of its orchestrated steps are still ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...

During replication, DNA polymerases are positioned on each strand of DNA . Using a microscope slide as an anchor, we tethered DNA to a bead and stretched it with a flow of solution. We tracked how the ...

The image you see here isn't of the USS Enterprise in warp, it's an image of DNA replication captured for the first time. The interesting part is that the replication of DNA isn't what scientists and ...

LA JOLLA, CA - April 14, 2011 - An enzyme essential for DNA replication and repair in humans works in a way that might be exploited as anti-cancer therapy, say researchers at The Scripps Research ...